Genetics of Rheumatoid Arthritis Study

Principal Investigator: Joseph Fanciullo, MD

Study Coordinator: Julie Kittelsrud, CNP

Sub-Investigators: Susan Weaver, CNP

Overview: The overall goal of this study is to map and eventually to identify the genes that regulate susceptibility to Rheumatoid Arthritis (RA) through a collection of family “trios.” The trios will consist of an adult individual diagnosed with RA and the individual’s two living biological parents.

RA is estimated to have a substantial genetic component, with a heritability of approximately 60%.

Inclusion Criteria:

• Males and females, ages 19 and older
• Diagnosis of RA based on American College of Rheumatology criteria
• Both biological parents must be available and willing to donate a blood sample

Exclusion Criteria:

• Diagnosis of psoriasis, inflammatory bowel disease or lupus in the RA patient only
• RA patient is known to be both RF and CCP negative
• To be determined by the study coordinator

Contact: Julie Kittelsrud, CNP
Phone:  (605) 322-3069
Email:   julie.kittelsrud@avera.org