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Research at Avera

Contact the Avera Research Institute

If you have questions about clinical trials, cancer research or other programs of the Avera Research Institute, we are located at 3720 W. 69th Street, Sioux Falls, SD, or you can call us at:


Since 1998, the Avera Research Institute has been a place where health care innovations are developed and tested. Not only does medical research add to the body of scientific knowledge, but participation in clinical trials gives Avera patients access to cutting-edge treatments.

Genetics & Personalized Medicine

Recognizing that the future of medicine and healthcare is in genomics and personalized medicine, Avera created the Avera Institute for Human Genetics (AIHG) in 2006. The state-of-the-art molecular genetics laboratory, located at 3720 W. 69th Street, focuses on DNA analysis and personalized medicine, which involves individualized medical recommendations based each patient's DNA profile.

The AIHG advances clinical and research efforts, partnering with national and international institutions, such as the University of Nebraska Medical Center, the University of Texas MD Anderson Cancer Center, and the Vrije University in Amsterdam, The Netherlands.

Clinical Research & Trials

A clinical research study (or trial) is designed to answer specific questions about drugs, vaccines, and medical devices, as well as new ways of using current treatments for other medical conditions. Clinical drug trials are used to determine if new treatments are both safe and effective, and are the safest way to find treatments that work.

By participating in national and international trials, Avera Research Institute offers patients cutting-edge treatment, prevention and diagnosis strategies.

Clinical Cancer Research

Until there’s a cure for cancer, each new drug and each new treatment represent new hope. Cancer research gives patients access to cutting-edge treatments. Research and clinical trials offer better outcomes and quality of life today, as well as hope for improved treatment and cures in the future.

The Avera Research Institute, in collaboration with the Avera Cancer Institute, has a very robust cancer research program with many cancer clinical trials. We regularly have approximately 100 open clinical studies through the National Cancer Institute and industry sponsors. Patients may also participate in investigator-initiated trials – studies in which Avera physicians propose their own ideas to research.

Additional Research Divisions

The Applied Research Division focuses on creating or inventing marketable products, and our scientists identify commercialization potential.

Live Better. Live Balanced. Avera.

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