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Avera Institute for Human Genetics

3720 W. 69th Street Suite 200
Sioux Falls, SD 57108
Phone: 605-322-3050

GDavies

Dr. Gareth Davies

Scientific Director

Gareth Davies, PhD, is a Human Molecular Geneticist with expertise in complex diseases and gene expression.

Research Interests

This information will be available soon.

Professional Memberships

  • International Society of Psychiatric Genetics
  • The American Society for Human Genetics
  • American Association of Immunologists
  • FASEB
  • AACP
  • The Obesity Society
  • Sigma Xi
  • Rho Chi
  • Kappa Psi

Publications

Abdellaoui A, Hottenga JJ, Xiao X, Scheet P, Ehli EA, Davies GE, Hudziak JJ, Smit DJA, Bartels M, Willemsen G, Brooks A, Sullivan PF, Smit JH, de Geus EJ, Phenninx BW, Boomsma D. Association Between Autozygosity and Major Depression: Stratification Due to Religious Assortment. Behav Genet. 2013;43(6):455-467. Click here for the abstract.

Groen-Blokhuis MM, Franic S, van Beijsterveldt CE, de Geus E, Bartels M, Davies GE, Ehli EA, Xiao X, Scheet PA, Althoff R, Hudziak JJ, Middeldorp CM, Boomsma DI. A prospective study of the effects of breastfeeding and FADS2 polymorphisms on cognition and hyperactivity/attention problems. Am J Med Genet B Neuropsychiatr Genet. 2013 Jul;162(5):457-65. Click here for the abstract.

Abdellaoui A, Hottenga JJ, Knijff PD, Nivard MG, Xiao X, Scheet P, Brooks A, Ehli EA, Hu Y, Davies GE, Hudziak JJ, Sullivan PF, van Beijsterveldt T, Willemsen G, de Geus EJ, Penninx BW, Boomsma DI. Population structure, migration, and diversifying selection in the Netherlands. Eur J Hum Genet. 2013 Mar 27. [Epub ahead of print] Click here for the abstract.

van Beijsterveldt CE, Groen-Blokhuis M, Hottenga JJ, Franić S, Hudziak JJ, Lamb D, Huppertz C, de Zeeuw E, Nivard M, Schutte N, Swagerman S, Glasner T, van Fulpen M, Brouwer C, Stroet T, Nowotny D, Ehli EA, Davies GE, Scheet P, Orlebeke JF, Kan KJ, Smit D, Dolan CV, Middeldorp CM, de Geus EJ, Bartels M, Boomsma DI. The Young Netherlands Twin Register (YNTR): Longitudinal Twin and Family Studies in Over 70,000 Children. Twin Res Hum Genet. 2013 Feb;16(1): 252-67. Click here for the abstract.

Geels LM, Groen-Blokhuis MM, van Beijsterveldt CE, Vink JM, Middeldorp CM, Bartels M, Nelson KA, Huizenga PE, Davies GE, Boomsma DI. Maternal prenatal smoking and offspring emotional problems: no moderating effect of maternal or child 5-HTTLPR genotype. Am J Med Genet B Neuropsychiatr Genet. 2012 Dec;159B(8):1009-12. doi: 10.1002/ajmg.b.32110. Epub 2012 Oct 22. Click here for the abstract.

Scheet P, Ehli EA, Xiao X, van Beijsterveldt CE, Abdellaoui A, Althoff RR, Hottenga JJ, Willemsen G, Nelson KA, Huizenga PE, Hu Y, Amos CI, Bartels M, Groen-Blokhuis MM, de Geus EJ, Hudziak JJ, Davies GE, Boomsma DI. Twins, tissue, and time: an assessment of SNPs and CNVs. Twin Res Hum Genet. 2012 Dec;15(6):737-45. Click here for the abstract.

Ehli EA, Abdellaoui A, Hu Y, Hottenga JJ, Kattenberg M, van Beijsterveldt T, Bartels M, Althoff RR, Xiao X, Scheet P, de Geus EJ, Hudziak JJ, Boomsma DI, Davies GE. De novo and inherited CNVs in MZ twin pairs selected for discordance and concordance on Attention Problems. Eur J Hum Genet. 2012 Oct;20(10):1037-43. Click here for the abstract.

Hu Y, Ehli EA, Hudziak JJ, Davies GE. Berberine and evodiamine influence serotonin transporter (5-HTT) expression via the 5-HTT-linked polymorphic region. Pharmacogenomics J. 2012 Oct;12(5):372-8. Click here for the abstract.

Hu Y, Ehli EA, Kittelsrud J, Ronan PJ, Munger K, Downey T, Bohlen K, Callahan L, Munson V, Jahnke M, Marshall LL, Nelson K, Huizenga P, Hansen R, Soundy TJ, Davies GE. Lipid-lowering effect of berberine in human subjects and rats. Phytomedicine. 2012 Jul 15;19(10):861-7. Click here for the abstract.

Hu Y, Ehli EA, Nelson K, Bohlen K, Lynch C, Huizenga P, Kittlelsrud J, Soundy TJ, Davies GE. Genotyping performance between saliva and blood-derived genomic DNAs on the DMET array: a comparison. PLoS One. 2012;7(3):e33968. Click here for the abstract.

Ehli EA, Hu Y, Lengyel-Nelson T, Hudziak JJ, Davies GE. Identification and functional characterization of three novel alleles for the serotonin transporter-linked polymorphic region. Mol Psychiatry. 2012 Feb; 17(2):185-192. Click here for the abstract.

Stoltenberg SF, Lehmann MK, Christ CC, Hersrud SL, Davies GE. Associations among types of impulsivity, substance use problems and Neurexin-3 polymorphisms. Drug Alcohol Depend. 2011 Dec 15;119(3):e31-8. Click here for the abstract.

Hu Y, Kutscher E, Davies GE. Berberine inhibits SREBP-1-related clozapine and risperidone induced adipogenesis in 3T3-L1 cells. Phytotherapy Res. 2010 Dec 24(12):1831-8. Click here for the abstract.

Albaugh MD, Harder VS, Althoff RR, Rettew DC, Ehli EA, Lengyel-Nelson T, Davies GE, Ayer L, Sulman J, Stanger C, Hudziak JJ. COMT Val158Met genotype as a risk factor for problem behaviors in youth. J Am Acad Child Adolesc Psychiatry. 2010 Aug;49(8):841-9. Click here for the abstract.

Hu Y, Davies GE. Berberine inhibits adipogenesis in high-fat diet-induced obesity mice. Fitoterapia. 2010 Jul;81(5):358-66. Click here for the abstract.

Kumar A, Yellepeddi VK, Davies GE, Strychar KB, Palakurthi S. Enhanced gene transfection efficiency by polyamidoamine (PAMAM) dendrimers modified with ornithine residues. Int J Pharm. 2010 Jun 15;392(1-2):294-303. Click here for the abstract.

Hu Y, Fahmy H, Zjawiony J, Davies GE. Inhibitory effect and transcriptional impact of berberine and evodiamine on human white preadipocyte differentiation. Fitoterapia. 2010 Jun;81(4):259-268. Click here for the abstract.

Hu Y, Davies GE. Berberine increases expression of GATA-2 and GATA-3 during inhibition of adipocyte differentiation. Phytomedicine. 2009 Sep;16 (9):864-73. Click here for the abstract.

Kutscher E, Davies GE. Pharmacogenomics: Has our history become Modern Medicine? S D Med. 2009 Apr:62(4);160-161.

Ehli EA, Lengyel-Nelson T, Hudziak JJ, Davies GE. Using a commercially available DNA extraction kit to obtain high quality human genomic DNA suitable for PCR and genotyping from 11-year-old saliva saturated cotton spit wads. BMC Res Notes. 2008 Dec 22;1(1):133. Click here to read the free article.

Davies GE, Locke SM, Wright PW, Li H, Hanson RJ, Miller JS, Anderson SK. Identification of bidirectional promoters in the human KIR genes. Genes Immun. 2007 Apr;8(3):245-53. Click here for the abstract.

Davies GE, Saleh A, Pascal V, Wright PW, Hodge DL, Cho EH, Lockett SJ, Abshari M, Anderson SK. Identification of probabilistic transcriptional switches in the Ly49 gene cluster: A eukaryotic mechanism for selective gene activation. Immunity. 2004 Jul;21(1):55-66. Click here for the abstract.

Pascal V, Davies GE, Anderson SK. A critical role for NFκB/p65 in establishing the Ly49 gene cluster. Clin Invest Med. 2004;27(4).

Anderson SK, Pascal V, Davies GE. A molecular explanation for stochastic receptor expression: probabilistic switches. Clin Invest Med. 2004;247(4).

Hessner MJ, Vaughan K, Meyer L, Davies GE, Nye S, Wang X, Ghosh S. Gene expression profiling in the diabetic prone (DP) and diabetic resistant (DR) biobreeding rat. Diabetes. 2002;51(Suppl 1):257S.

Davies GE, Sabatakos G, Cryer A, Ramji DP. The Ovine CCAAT-Enhancer Binding Protein delta Gene: Cloning, Characterization, and Species-Specific Autoregulation. Biochem Bioph Res Co. 2000 May; 271(2):346-352. Click here for the abstract.

Sabatakos G, Davies GE, Grosse M, Cryer A, Ramji DP. Expression of the genes encoding the CCAAT-enhancer binding protein isoforms in the mouse mammary gland during lactation and involution. Biochem J. 1998 Aug;334(1):205-210. Click here for the abstract.