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Oncology Studies

Following is a complete list of oncology studies currently enrolling patients.

Avera Cancer Institute Sioux Falls

Brain Cancer Studies

Breast Cancer Studies

Colon Cancer Studies

Esophageal Cancer Studies

Gynecologic Cancer Studies

Leukemia Studies

Liver Cancer Studies

  • CTSU C80802 -- Phase III Randomized Study of Sorafenib plus Doxorubicin versus Sorafenib in Patients with Advanced Hepatocellular Carcinoma (HCC) 

Lung Cancer Studies

Lymphoma Studies

Multiple Myeloma

  • Randomized, Double-Blind, Multi-Center Study of Denosumab Compared with Zoledronic Acid in the Treatment of Bone Disease in Subjects with Newly Diagnosed Multiple Myeloma

Prostate Cancer Studies

Renal/Urinary Tract Cancer Studies

Transplant/Transfusion Studies

  • Filgrastim-Mobilized Peripheral Blood Stem Cells for Allogeneic Transplantation with Unrelated Donors

Cancer Control Studies

Cancer Registry Studies

  • Development and Implementation of the Breast Cancer Collaborative Registry (BCCR)
  • Breast Specimen Bank for Genetic and Genomic Investigation (BSB-B1)
  • A Registry of Sipuleucel-T Therapy in Men with Advanced Prostate Cancer (Closed to Enrollment)
  • Studying Interventions for Managing Patients with Chronic Myeloid Leukemia in Chronic Phase: The 5-Year Prospective Cohort Study (SIMPLICITY)
  • Prospective, Non-Interventional Study of Disease Progression and Treatment of Patients with Polycythemia Vera in United States Academic or Community Clinical Practices (REVEAL) 
  • Development and Implementation of the Thyroid Tumor and Cancer Collaborative Registry (TCCR) 
  • Paroxysmal Nocturnal Hemoglobinuria (PNH) Registry 
  • A Next Generation Sequencing Study Designed to Elucidate the Molecular Basis of Metastatic Brain Relapse in Breast Cancer Survivors
  • Identifying Molecular Drivers of Cancer 

    Avera Cancer Institute Aberdeen

    Breast Cancer Studies

    Colon Cancer Studies

    Lung Cancer Studies

    Multiple Myeloma

    Renal/Urinary Tract Cancer Studies

    Cancer Control Studies

    Cancer Registry Studies


      Avera Cancer Institute Mitchell


      Currently Enrolling Studies

      Clinical Drug Research
      The Avera Research Institute offers a variety of clinical trials on disease treatment and prevention, as well as health improvement.

      Current clinical trials

      Clinical Cancer Research
      Avera has a robust cancer research program. Visit the link below to view a list of cancer trials currently open to enrollment.

      Current cancer trials

      Avera Institute for Human Genetics

      The Avera Institute for Human Genetics (AIHG) is the premier genetics laboratory in the region.

      Avera IHG details

      National Institute of Mental Health Outreach Partnership Program

      View updates regarding our partnership program and other available resources.