Charles W. Murphy

Charles W. Murphy, MD

Radiation Oncology and Oncology

"It’s important that patients feel comfortable and confident with me as their physician. I help patients understand that although I am treating their cancer diagnosis, I’m also interested in the other aspects of their lives, such as their professions, hobbies, future plans and dreams, as well as anything else being impacted by their health condition."

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Office Information

About Me

Dr. Murphy is the only doctor in his family. When he was a young man, his mother was diagnosed with breast cancer. Watching her go through that experience — and finding victory — inspired him to explore medicine as a profession.

Today, Dr. Murphy provides compassionate cancer treatment through radiation oncology at Avera Medical Group Radiation Oncology in Sioux Falls, SD. The clinic is conveniently located inside the Avera Cancer Institute, a facility completely dedicated to complete cancer care.

Compassionate Cancer Treatment

Dr. Murphy finds medicine a unique and challenging study that allows him and fellow providers to have a positive impact on the lives of people. As a radiation oncologist, he sees patients of all ages facing all kinds of cancers, such as breast, colon, pancreas, lung, prostate and more.

According to Dr. Murphy, one reason why Avera stands out in cancer care is their dedication to providing the most effective care through the availability to the latest technology, including the Elekta Versa HD™ linear accelerator and Gamma Knife.

“Precise radiation oncology, like that offered at Avera, allows me to give my patients the very best care,” said Dr. Murphy. “Avera has gone to great lengths to offer exceptional cancer care in this region.”

Good Health Care Advice

Getting your recommended screenings on time can help you and your primary provider find and initiate treatment during the most treatable stages of cancer.

So, if something feels off regarding your health, Dr. Murphy strongly suggests seeing a provider as soon as possible.

“Receiving cancer treatment can be very stressful and confusing for many patients. I encourage patients to never hesitate to discuss any concerns or questions with me,” said Dr. Murphy. “Open communication often helps patients and their families feel more at ease.”

Active Lifestyle

When Dr. Murphy isn’t at work, he enjoys playing basketball as well as the drums. He and his wife love to travel, hike and spend time outdoors. In addition, his Christian faith plays an important role in his life, so he appreciates the Gospel-centered mission of Avera.



University of Iowa Carver College of Medicine, Iowa City, Medical School


UnityPoint Health/University of Iowa, Des Moines, Internal Medicine

University of Iowa Hospitals and Clinics, Iowa City, Radiation Oncology

Teaching or Professional Positions

  • Assistant Professor of Radiation Oncology - Marshall University School of Medicine
  • Radiation Oncology Fellowship Rotation Director - Marshall University School of Medicine
  • Medical Student Mentor in Radiation Oncology - Marshall University School of Medicine

Professional Memberships

  • American Society for Radiation Oncology
  • American Brachytherapy Society
  • Edwards Comprehensive Cancer Center Committee on Cancer
  • Edwards Comprehensive Cancer Center Oncology Clinical Research Committee
  • Edwards Comprehensive Cancer Center Radiation Safety Committee
  • Edwards Comprehensive Cancer Center Committee on HPV Awareness & Prevention 

Honors, Awards, etc.

Chief Resident, University of Iowa Department of Radiation Oncology 2011-2012


American Board of Radiology - Radiation Oncology

This directory contains information about the provider members of Independent Health Care Associates, Avera Health and all Avera entities, members of the Avera Medical Group, and employed select providers with Avera McKennan, Sioux Falls, SD and Avera Marshall, Marshall, MN and physicians with hospital privileges at Avera St. Luke's, Aberdeen, SD; Avera Sacred Heart, Yankton, SD; Avera Queen of Peace, Mitchell, SD; Avera St. Mary's, Pierre, SD.

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Avera is a health ministry rooted in the Gospel. Our mission is to make a positive impact in the lives and health of persons and communities by providing quality services guided by Christian values.