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Jason L. Picconi

Jason L. Picconi, MD, PhD, FACMG, FACOG

Obstetrics/Gynecology, Perinatology, Maternal-Fetal Medicine, and Genetics

Office Information

About Me

Professional Focus

Dr. Picconi is a board-certified expert in the diagnosis and management of both maternal and fetal complications of pregnancy. Additionally, he is a board-certified expert in diagnosing and managing prenatal genetic syndromes in unborn babies, as well as helping mothers manage their genetic conditions during pregnancy.

Special Interests

  • Management of maternal inborn errors of metabolism
  • Diagnosis of fetal genetic disorders
  • Preconception counseling for maternal medical and genetic conditions

Personal Interests

When not caring for patients, Dr. Picconi serves as a Flight Surgeon in the Army National Guard.

He enjoys free time with his wife and two children and also looks forward to spending time outdoors, specifically hunting, fishing and camping when time and weather allow.



Creighton University School of Medicine, Omaha, Nebraska, Medical School


Wayne State University / Detroit Medical Center, Detroit, Michigan, Obstetrics and Gynecology


University of Iowa Hospitals & Clinics, Iowa City, IA, Medical Genetics

University of Iowa Hospitals & Clinics, Iowa City, IA, Maternal-Fetal Medicine

Professional Memberships

  • American College of Obstetricians and Gynecologists
  • American College of Medical Genetics and Genomics
  • Society for Maternal-Fetal Medicine
  • American Institute of Ultrasound in Medicine
  • International Society for Prenatal Diagnosis 
  • International Society for Ultrasound in Obstetrics and Gynecology
  • American Society of Human Genetics
  • American Medical Association
  • South Dakota State Medical Association
  • South Dakota Perinatal Association 


  • American Board of Medical Genetics and Genomics 2013
  • American Board of Obstetrics and Gynecology (General OB/GYN) 2015
  • American Board of Obstetrics and Gynecology (Maternal Fetal Medicine) 2017


  • South Dakota Board of Medical and Osteopathic Examiners
  • Iowa Board of Medicine
  • Minnesota Board of Medical Practice

Medical Research & Clinical Trials


Picconi JL, Muff-Luett MA, Wu D, Bunchman E, Schaefer F, Brophy PD. Kidney-specific expression of GFP by in-utero delivery of pseudotyped adeno-associated virus 9. Molecular Therapy – Methods & Clinical Development. 2014; 14014. PMID# 

Scheuerle A, Picconi JL, Neidich J, Panny S, Pletcher BA, Randolph LM, Trapane P, Trotter TL. The Childless Man. American Journal of Medical Genetics Part A. 2013; 9999 (1): 1. PMID 24311465.

Kamel MA, Picconi JL*, Lara-Castillo N, Johnson ML. Activation of beta-catenin signaling in MLO-Y4 osteocytic cells versus 2T3 osteoblastic cells by fluid flow shear stress and PGE2: Implications for the study of mechanosensation in bone. Bone. 2010; 47 (5): 872-881. PMID 20713195.

Kaur S, Picconi JL*, Chadha R, Kruger M, Mari G. Biophysical Profile in the Treatment of Intrauterine Growth-Restricted Fetuses who Weigh <1000 g. American Journal of Obstetrics and Gynecology. 2008; 199 (3): 264-265. PMID 18771977. 

Picconi JL, Kruger M, Mari G. Ductus Venosus S-Wave / Isovolumetric A-Wave (SIA) Index and A-Wave Reversed Flow in Severely Premature Growth-Restricted Fetuses. Journal of Ultrasound in Medicine. 2008; 27 (9): 1283-1289. PMID 18716137. 

Picconi JL, Hanif F, Drennan K, and Mari G.  The Transitional Phase of Ductus Venosus Reversed Flow in Severely Premature IUGR Fetuses. American Journal of Perinatology. 2008; 25 (4): 199-204. PMID 18548391.

Review Articles

Picconi JL and Mari G. Classification and Management of IUGR Fetuses. Fetal and Maternal Medicine Review. 2008; 19 (3): 1-17.

Mari G and Picconi JL. Doppler Vascular Changes in Intrauterine Growth Restriction. Seminars in Perinatology 2008; 32 (3): 182-189. PMID 18482619.

Johnson ML, Picconi JL, Recker RR. The Gene for High Bone Mass.  Endocrinologist. 2002; 12 (5): 445-453.

This directory contains information about the provider members of Independent Health Care Associates, Avera Health and all Avera entities, members of the Avera Medical Group, and employed select providers with Avera McKennan, Sioux Falls, SD and Avera Marshall, Marshall, MN and physicians with hospital privileges at Avera St. Luke's, Aberdeen, SD; Avera Sacred Heart, Yankton, SD; Avera Queen of Peace, Mitchell, SD; Avera St. Mary's, Pierre, SD.

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