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John F. Wagener

John F. Wagener, MD, FACC, FSCAI

Interventional Cardiology
4.9 / 5 (Based on 284 Ratings) Read Reviews | Learn More

"Serving patients is my favorite part of my job. When something is wrong with your cardiovascular system, it can be scary, so being a source of comfort and expertise is rewarding."

Office Information

About Me

Look to Dr. Wagener for compassionate and comprehensive cardiovascular care services at Avera Heart Hospital.
He provides care for patients of any age, with a special focus on the diagnosis and treatment of heart disease and related conditions. He can help patients with lifestyle changes or procedures including angiograms and cardiac catheterization as well as other steps to address heart conditions and vascular illnesses.

Special Interests

  • Transcatheter aortic valve replacement (TAVR)
  • Balloon aortic valvuloplasty
  • MitraClip
  • Transcatheter mitral valve replacement
  • Transcatheter tricuspid valve replacement
  • Balloon mitral valvuloplasty
  • Paravalvular leak closure
  • Alcohol septal ablation
  • PFO closure
  • Atrial septal defect closure (ASD)
  • Ventricular septal defect closure (VSD)
  • Pulmonary vein stenting
  • Coronary artery angioplasty and stenting
  • Coronary atherectomy
  • Watchman
  • Impella 



University of North Dakota School of Medicine, Grand Forks, ND, Medical School


Duke University Medical Center, Durham, NC, Internal Medicine


Cleveland Clinic Foundation, Cleveland, OH, Cardiovascular Medicine

Cleveland Clinic Foundation, Cleveland, OH, Interventional/Structural Cardiology


December 13, 2021
Yeah, I was very pleased with my report and my time there. Thank you.
November 23, 2021
He listened to what I had to say and made sure I understood what he said
November 22, 2021
Very knowledgeable staff. Everyone explained what was being done very well. Was very impressed.
November 22, 2021
That was all everybody was very professional and courteous and stuff. It was a nice experience.
November 22, 2021
My meeting with Dr. Wagener was scheduled to be a half hour discussion of my health issues. We spent almost an hour covering everything in detail. He was very thoroughly, was very good at answering my questions and he listen to what I had to say. And I responded appropriately and respectfully, but with with good information, regarding the issues and concerns and comments and he was very respectful of my opinion, wild the same time, providing me with very good and useful information. I was very impressed with the way the morning went. Thank you.
November 19, 2021
I would recommend you to anyone. Thank you.
November 19, 2021
Everybody explained everything very well. With what they were doing that day. All the tests they are running. I was extremely impressed and everything was handled with ease. The only thing I would say I didn't like as a lot of the waiting in between. So if they could find a way to make that better, that would be great. Other than that, my experience was wonderful.
November 18, 2021
He was a very helpful. We understand everything that he explained to us, and he was very kind. We appreciate his knowledge and he was very professional. Thank you.
November 17, 2021
Staff was very pleasant and helpful. Nurses/Doctor were very attentive and did not rush any part of the appointment.
November 09, 2021
I was very much satisfied with the doctor and his nurse. They are very accommodating. They listened to what you had to say
September 30, 2021
I was very impressed with the Dr. I was very impressed with the facilities. You guys did an amazing job. I would highly recommend you to anyone. That I come in contact with. Super job, and thank you very much.
September 30, 2021
Hi, I thought that doctor was very courteous. Very nice. Very thorough. And his nurses, very nice. Yes. Good job. Yes, and a great place to go. Thank you much.
September 28, 2021
This staff was clear, informative, caring, knowledgeable and my mind at ease and I know I'm good hands Dr. Wagener.
September 23, 2021
DR. Wagener was impressive and knowledgeable His nurse was awesome and nice Echo went well and found out we worked at the same place @ the same time had a nice visit Don't have their names :( Over all experience, confidence in the care, and knowledge a 10 Thank you
September 15, 2021
Everything was good!!
September 07, 2021
I was very impressed with the helpfulness of the people that were there, both their information people and all of them including the provider. So that was so impressive. I don't know if I was told not to do caffeine before going there, but I think it was probably too late to do a test that day anyway, otherwise I ended up having to come back, but just because it's so far. Then it became more of a challenge for me. But otherwise everything was fantastic. Thanks so much. Bye.
September 02, 2021
Yes, I think my my check up was very good. I was, I didn't come with any problem at all. And he, he knew about all my other problem, my past problems, and we talked about them. And so I was, I was pleased to know that he knew about my other problems I had besides the heart problem and, and I was glad to know that both of my son's could come in and, and hear the doctor tell me everything because I cannot remember everything very well anymore.
August 31, 2021
Dr. Wagener was kind and professional. He explained my current problem completely and even drew a picture of the heart and how the PFO would be fixed. I immediately liked him, as did my husband. I feel I will get quality care when I do the procedure from him and the hospital.
August 24, 2021
Dr. Wagener was the first physician to ever make me feel like he actually read my chart. I wasn't sure I even really needed to see a cardiologist, but he talked me through how my symptoms could lead back to the heart and made a plan that I feel is very thorough. After leaving I told my husband I wish he could be my primary care provider. 10/10 would recommend him to anyone. He's wonderful!
August 23, 2021
Timely manner. All involved professional.
August 18, 2021
Yes, our experience at the hospital was very positive. Everybody was real nice, very informative. But we did wait quite a while in the waiting room, after the nurses took our blood pressures and heart rates and stuff like that, before the doctor come in.
August 18, 2021
Everyone was very nice and helpful, very refreshing
August 16, 2021
Well, when I first walked in everybody was so nice and pleasant. Made sure you were taken care of and they talked to you and they were telling you what they were doing. It was very informative. I could not have asked for anything better to be approach done. That was just - it made my day. Thanks.
July 30, 2021
Yeah, I would say for a first time visitor, I thought I was greeted very well, certainly by name, it was quick. Nobody, I wasn't waiting very long, so I'm very, very satisfied, and look forward to staying what the next step is. Thank you.
July 26, 2021
Service was friendly and professional. I was seen on time which to me says that you respect my time the way that I appreciate yours.
July 20, 2021
I would like to thank each and every healthcare worker that I encountered at North Central Heart. I was very nervous and anxious, but each person helped me understand what was going and they treated me with respect and consideration. Dr. Wagener was very patient and calm. He answered any questions I had. He listened attentively and with an excellent bedside manner. I appreciate all the time, effort, and expertise I received at your facility.
July 15, 2021
Dr. Wagener was excellent. He took the time I needed. He understood that was my first time being with that Avera Clinic or whatever that was. But he was excellent. And I would highly recommend him to anyone who needed medical care with somebody who could actually take the time to explain to us what it is we need.
July 13, 2021
Both the clerical, and the nursing, doctor, the echocardiogram tech, all were absolutely fantastic. Very responsive to my questions and just, just great overall. Thank you.
July 08, 2021
Dr. Wagener was most excellent and I think he's a great human, and I really appreciate everything he did for me. Thanks.
June 15, 2021
The Doctor I saw made all the difference!
May 25, 2021
very good
May 17, 2021
Every doctor and treated us and our questions with respect and care.
May 11, 2021
The explanation of ALL the different approaches for my situation was surprising and helpful.
April 28, 2021
Everyone was friendly, helpful, and professional. Loved that it was on time and seemed very efficient
April 26, 2021
Excellent service by everyone nurses were exceptional helpful and kind
April 22, 2021
everybody was very nice
April 19, 2021
Yes, I was very, very satisfied with everything, basically. The help was all good, polite. The doctors were superb. It was a very good, very well explained as to what we was going to do before, and that was very satisfying. Thank you.
April 01, 2021
I was treated with very much care and concern. I was treated respectfully and listened to and I appreciated that very much.
March 12, 2021
I felt that Dr. Wagener truly cared about my status and my future. He was extremely aware of why I came in to the hospital and what we needed to do. And the follow up was great.
March 09, 2021
The nurses who took care of me were awesome!!!! Take care of the nurses with great wages and benefits. They gave me alot of care.

This directory contains information about the provider members of Independent Health Care Associates, Avera Health and all Avera entities, members of the Avera Medical Group, and employed select providers with Avera McKennan, Sioux Falls, SD and Avera Marshall, Marshall, MN and physicians with hospital privileges at Avera St. Luke's, Aberdeen, SD; Avera Sacred Heart, Yankton, SD; Avera Queen of Peace, Mitchell, SD; Avera St. Mary's, Pierre, SD.

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