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John F. Wagener

John F. Wagener, MD, FACC, FSCAI

Interventional Cardiology

"Serving patients is my favorite part of my job. When something is wrong with your cardiovascular system, it can be scary, so being a source of comfort and expertise is rewarding."

Office Information

About Me

Look to Dr. Wagener for compassionate and comprehensive cardiovascular care services at Avera Heart Hospital.
He provides care for patients of any age, with a special focus on the diagnosis and treatment of heart disease and related conditions. He can help patients with lifestyle changes or procedures including angiograms and cardiac catheterization as well as other steps to address heart conditions and vascular illnesses.

Special Interests

  • Transcatheter aortic valve replacement (TAVR)
  • Balloon aortic valvuplasty
  • MitraClip
  • Transcatheter mitral valve replacement
  • Tracscatheter tricuspid valve replacement
  • Balloon midial valvuplasty
  • Paravalvular leak closure
  • Alcohol septal ablation
  • PFO closure
  • Atrial septal defect closure (ASD)
  • Ventricular septal defect closure (VSD)
  • Pulmonary vein stenting
  • Coronary artery angioplasty and stenting
  • Coronary atherectomy
  • Watchman
  • Impella 



University of North Dakota School of Medicine, Grand Forks, ND, Medical School


Duke University Medical Center, Durham, NC, Internal Medicine


Cleveland Clinic Foundation, Cleveland, OH, Cardiovascular Medicine

Cleveland Clinic Foundation, Cleveland, OH, Interventional/Structural Cardiology

This directory contains information about the provider members of Independent Health Care Associates, Avera Health and all Avera entities, members of the Avera Medical Group, and employed select providers with Avera McKennan, Sioux Falls, SD and Avera Marshall, Marshall, MN and physicians with hospital privileges at Avera St. Luke's, Aberdeen, SD; Avera Sacred Heart, Yankton, SD; Avera Queen of Peace, Mitchell, SD; Avera St. Mary's, Pierre, SD.

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