Skip to Content
Mark J. Jameson

Mark J. Jameson, MD, PhD, FACS

Head and Neck Surgery, Ear, Nose & Throat, and Otolaryngology

"When someone receives a devastating diagnosis or is facing a profound functional concern, our work is more than solving a problem; it’s offering hope for survival and the most ideal outcome."

View my videos

Office Information

About Me

A passion for science, especially for the biology of the human body, drew Mark Jameson, MD, PhD, to a career in medicine. During his education, his great appreciation for the functions of the head and neck — breathing, communication, eating — inspired him to pursue otolaryngology.

Today, Dr. Jameson offers his expertise and services as a head and neck surgeon at Avera Medical Group Ear, Nose & Throat in Sioux Falls, SD.

“My team and I keep quality of life at the forefront of each patient case. We work to achieve the most ideal outcome for each individual,” he said.

Treating Complex Conditions of the Ears, Nose and Throat

Dr. Jameson offers both surgical and nonsurgical solutions for a variety of conditions related to the ear, nose and throat, including:

  • Mouth, throat, voicebox and sinus cancers
  • Head and neck skin cancers including melanoma
  • Cancers and benign tumors of the salivary glands
  • Issues related to smell, taste and swallowing

Innovative Care for Ideal Outcomes

Caring for the ears, nose and throat is a sophisticated art, which is why Dr. Jameson and his team use robotic technology and the latest techniques to treat patients.

“Patients who’ve survived a head or neck cancer or an accident worry about having a situation that affects their taste or ability to talk,” said Dr. Jameson. “We can treat these effects to improve their quality of life.”

One technique Dr. Jameson frequently uses for patients with a life-limiting condition is microvascular free tissue transfer. A piece of tissue is taken from another part of the body and reconstructed into the affected head and neck area. Blood flow is reestablished to the tissue to restore function.

Active Lifestyle

When Dr. Jameson isn’t at work, he enjoys spending time with his family. They like to experience new cultures through their travels, and stay active by engaging in outdoor activities.



Medical University of South Carolina, Charleston SC, Medical School


University of Virginia Health System, Charlottesville VA, Otolaryngology – Head & Neck Surgery


University of Iowa Hospitals & Clinics, Iowa City IA, Head & Neck Oncologic and Reconstructive Surgery

Professional Memberships

  • American Academy of Otolaryngology – Head and Neck Surgery
  • American Association for Cancer Research
  • American College of Surgeons
  • American Head and Neck Society


  • American Board of Otolaryngology – Head and Neck Surgery

This directory contains information about the provider members of Independent Health Care Associates, Avera Health and all Avera entities, members of the Avera Medical Group, and employed select providers with Avera McKennan, Sioux Falls, SD and Avera Marshall, Marshall, MN and physicians with hospital privileges at Avera St. Luke's, Aberdeen, SD; Avera Sacred Heart, Yankton, SD; Avera Queen of Peace, Mitchell, SD; Avera St. Mary's, Pierre, SD.

Non-Avera web sites (e.g., Facebook, Twitter, etc.) linked to from this Web page, including any blogs or other personal, networking or social media Web sites, are not affiliated with, nor endorsed by any Avera facility. Opinions, views, and comments posted on these Web sites are not Avera's.  Avera assumes no legal liability or responsibility for the accuracy, completeness, or usefulness of any information, product, or process disclosed on these sites. The opinions of those posting comments, views or opinions on these sites do not necessarily state or reflect those of Avera and shall not be used for advertising or product endorsement purposes.

Moving Health Forward

Avera is a health ministry rooted in the Gospel. Our mission is to make a positive impact in the lives and health of persons and communities by providing quality services guided by Christian values.

© 2022 Avera Health, Sioux Falls, SD. All Rights Reserved.