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Michelle L. Bryan

Michelle L. Bryan, MD, PhD

Breast Surgery

"I want my patients to know that I'm going to take care of them no matter what, and I want to be a partner in making the best health care decisions for them. The hugs I get from patients, that relationship, is the best part of what I do."

Office Information

About Me

Are you facing a breast cancer diagnosis? If surgery is in your oncology treatment plan, trust Michelle Bryan, MD, PhD, to be there for you with expert and specialized surgery options. Practicing at Avera Medical Group Comprehensive Breast Care in Sioux Falls, SD, Dr. Bryan works hand-in-hand with your oncology team to ensure the best protocol steps for your individual diagnosis, cancer stage and tumor location.

Expert Surgery Treatments for Breast Cancer

Fellowship-trained, Dr. Bryan works together with world-class breast cancer experts at Avera Medical Group Oncology & Hematology in Sioux Falls, part of the Avera Cancer Institute. With her extensive experience, you can count on Dr. Bryan to recommend the most appropriate, effective breast cancer surgery options for you, while considering the best possible cosmetic results.

Her specialized training in surgical procedures includes:

  • Electron-based intraoperative radiation therapy (IORT) – Includes radiation during surgery which may eliminate the need for additional radiation or shorten the course of radiation
  • Oncoplasty – Combines techniques for removing cancer along with plastic surgery methods to improve the appearance of breasts
  • Lumpectomy – Conserves the breasts while providing the same recurrence prevention as mastectomy
  • Nipple-sparing mastectomy – Preserves the nipple and skin of the breast for future reconstruction
  • Hidden Scar™ – Removes the tumor and a slight amount of surrounding tissue through a small incision

Comprehensive Care for Breast Cancer

Benefit from multidisciplinary approach at Avera, in which a team of breast cancer experts meet weekly to discuss the best treatment options for your specific type of breast cancer. Dr. Bryan also recognizes the benefits of treating the side effects of cancer surgery through integrative medicine, so that you can experience a better quality of life.

“Find joy and gratitude in every moment, as this affects your overall health and life,” she adds as advice to patients facing cancer treatments. She is currently involved in quality performance measures research surrounding the delivery and efficiency of breast cancer surgery, and she participates in ongoing clinical trials at Avera.

Active Lifestyle

In her free time, Dr. Bryan enjoys being outdoors with her husband and son, planting and canning garden produce, raising animals and fostering a strong spiritual environment for her family.



Wake Forest University School of Medicine, Winston-Salem, NC, Medical School


Wake Forest Baptist Health, Winston-Salem, NC, General Surgery


Wake Forest Baptist Health, Winston-Salem, NC, Surgical Education

Cleveland Clinic at Akron General, Akron, OH, Breast Surgery Oncology

Professional Memberships

  • American College of Surgeons
  • American Society of Breast Surgeons

Honors, Awards, etc.

  • PhD - Department of Infectious Diseases and Microbiology, Graduate School of Public Health
  • Academic Entrepreneurship - Joseph M. Katz Graduate School of Business


Eligible - American Board of Surgery

This directory contains information about the provider members of Independent Health Care Associates, Avera Health and all Avera entities, members of the Avera Medical Group, and employed select providers with Avera McKennan, Sioux Falls, SD and Avera Marshall, Marshall, MN and physicians with hospital privileges at Avera St. Luke's, Aberdeen, SD; Avera Sacred Heart, Yankton, SD; Avera Queen of Peace, Mitchell, SD; Avera St. Mary's, Pierre, SD.

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Avera is a health ministry rooted in the Gospel. Our mission is to make a positive impact in the lives and health of persons and communities by providing quality services guided by Christian values.

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