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Michelle L. Bryan, MD, PhD

Breast Surgery
4.9 / 5 (Based on 113 Ratings) Learn More

"I want my patients to know that I'm going to take care of them no matter what, and I want to be a partner in making the best health care decisions for them. The hugs I get from patients, that relationship, is the best part of what I do."

Office Information

About Me

Are you facing a breast cancer diagnosis? If surgery is in your oncology treatment plan, trust Michelle Bryan, MD, PhD, to be there for you with expert and specialized surgery options. Practicing at Avera Medical Group Comprehensive Breast Care in Sioux Falls, SD, Dr. Bryan works hand-in-hand with your oncology team to ensure the best protocol steps for your individual diagnosis, cancer stage and tumor location.

Expert Surgery Treatments for Breast Cancer

Fellowship-trained, Dr. Bryan works together with world-class breast cancer experts at Avera Medical Group Oncology & Hematology in Sioux Falls, part of the Avera Cancer Institute. With her extensive experience, you can count on Dr. Bryan to recommend the most appropriate, effective breast cancer surgery options for you, while considering the best possible cosmetic results.

Her specialized training in surgical procedures includes:

  • Electron-based intraoperative radiation therapy (IORT) – Includes radiation during surgery which may eliminate the need for additional radiation or shorten the course of radiation
  • Oncoplasty – Combines techniques for removing cancer along with plastic surgery methods to improve the appearance of breasts
  • Lumpectomy – Conserves the breasts while providing the same recurrence prevention as mastectomy
  • Nipple-sparing mastectomy – Preserves the nipple and skin of the breast for future reconstruction
  • Hidden Scar™ – Removes the tumor and a slight amount of surrounding tissue through a small incision

Comprehensive Care for Breast Cancer

Benefit from multidisciplinary approach at Avera, in which a team of breast cancer experts meet weekly to discuss the best treatment options for your specific type of breast cancer. Dr. Bryan also recognizes the benefits of treating the side effects of cancer surgery through integrative medicine, so that you can experience a better quality of life.

“Find joy and gratitude in every moment, as this affects your overall health and life,” she adds as advice to patients facing cancer treatments. She is currently involved in quality performance measures research surrounding the delivery and efficiency of breast cancer surgery, and she participates in ongoing clinical trials at Avera.

Active Lifestyle

In her free time, Dr. Bryan enjoys being outdoors with her husband and son, planting and canning garden produce, raising animals and fostering a strong spiritual environment for her family.



Wake Forest University School of Medicine, Winston-Salem, NC, Medical School


Wake Forest Baptist Health, Winston-Salem, NC, General Surgery


Wake Forest Baptist Health, Winston-Salem, NC, Surgical Education

Cleveland Clinic at Akron General, Akron, OH, Breast Surgery Oncology

Professional Memberships

  • American College of Surgeons
  • American Society of Breast Surgeons

Honors, Awards, etc.

  • PhD - Department of Infectious Diseases and Microbiology, Graduate School of Public Health
  • Academic Entrepreneurship - Joseph M. Katz Graduate School of Business


Eligible - American Board of Surgery


November 22, 2020
Upon leaving the clinic (with my big pink bag announcing I had cancer), I felt a sense of peace and security....that I could handle this and had great, caring people helping me.
November 21, 2020
The doctor, the receptionists, the nurse and the navigator were the most kind caring people. Couldn't ask for any better treatment.
November 21, 2020
A difficult situation was made so much better by her calm, caring spirit.
November 20, 2020
As always, treatment here is top shelf!
November 20, 2020
Dr. Bryan has to be one of the most caring, compassionate Drs I have ever met. The concern she shows to her patients is unbelievable.
November 15, 2020
Very satisfied with all great people
November 14, 2020
Dr Bryan has a lot of knowledge and I feel very confident with her.
November 14, 2020
All staff were so welcoming and friendly. They worked to accommodate my two appointments so they were scheduled close together as we live 2 1/2 hrs away from SF. Wonderful experience and I will be back every six months.
November 13, 2020
Everyone was very pleasant.
October 19, 2020
Dr Bryan took the time to answer my questions and explain things to me. In addition she was very kind.
October 12, 2020
Excellent care fine facility & staff
October 10, 2020
Post op visit. My surgeon had retired and this surgeon had taken her patients. Considering that this physician had not performed my surgery, I thought she spent much time with me answered questions and gave me pointers to remain healthy.
September 19, 2020
All of the staff showed compassion
September 16, 2020
Have always had a positive experience with staff at Avera. They go out of their way to reassure you and make you comfortable.
September 10, 2020
First time there everything and everyone was great
September 05, 2020
Greatest medical care ever.I recommend Avera all the time.
August 30, 2020
I've always had great service from Avera, the doctors and nurses. I would highly recommend Avera to all my friends and family.
August 21, 2020
Dr. Bryan is a good listener!
August 18, 2020
I have always received excellent and exceptional care all throughout my Avera experiences. This experience was exceptional!!
August 03, 2020
great service and care
July 25, 2020
Dr. Brien was incredible. She was thoughtful, kind and reassuring.
July 23, 2020
Excellent staff and Dr.
July 22, 2020
I have nothing but good things to say about Dr. Bryan. She was extremely helpful to me.
July 22, 2020
everyone was wonderful and friendly and had a very positivist attitude
July 15, 2020
The entire experience was exceptional. From the extra precautions due to COVID to the care and respect the entire morning. I have already recommended the doctors and techs I came in contact with.
July 03, 2020
The prairie center is an amazing place!
June 29, 2020
I went with an open mind with needing a new doctor - so far I am happy
June 27, 2020
Always feel welcome and well taken care of when visiting this clinic.
June 22, 2020
Very impressed and thankful for the excellent care
June 18, 2020
Happy she made time to get me with short notice.
May 24, 2020
Avera is the best
May 15, 2020
Dr. Bryan is just a super person. I felt very comfortable with her.
May 15, 2020
Felt reassured and totally cared for
May 13, 2020
This was my first appointment with Dr. Bryan as my initial surgeon was someone else. I am very impressed with Dr. Bryan and look forward to my continued patient care in her hands. I immediately felt her warmth and caring and came away feeling as though she has been my doctor since day one. Thank you, Dr. Bryan!
May 08, 2020
I give a full 10! Dr.Bryan was very professional. She took the time to explain everything and did a phenomenal job surgery wise. I was so pleased with how everyone in the facilitly was so friendly and helpful! Top of the line. I appreciate it so much.
April 03, 2020
Im always happy with my Avera Hospital
April 02, 2020
She was very informative and caring
March 31, 2020
I would recommend this medical group, they were very caring and concern about their patients.
March 21, 2020
Everyone was just wonderful
March 20, 2020
I have NEVER had a better experience with a group of medical professionals. Everyone I've met has been the most caring group of individuals. Every step of the way I've felt supported and that they truly care. These people (women) need the highest praises that you can give them. I would like to thank each and every one of them. I'm hoping they all knew how much I appreciated every single one of them
March 13, 2020
I will always be a Avera customer
March 07, 2020
Dr Bryan is get & she knows her stuff. Made sure all my questions were answered too. I trust her to handle my care.
March 01, 2020
I absolutely loved Dr. Bryan, she was more than i had hoped for in a doctor! Highly recommend her!
February 25, 2020
Dr. Bryan explained ever thing, in a way that i understood what she was talking about , ,i have much confermence in her , ,.very down to earth person.
February 19, 2020
the Secretary when I called, did always seem to have the answers I needed and didn't seem too concerned
January 31, 2020
I could hear everything the nurse was saying in the room next to me. Not good for privacy and I worried that they could hear my personal information too

This directory contains information about the provider members of Independent Health Care Associates, Avera Health and all Avera entities, members of the Avera Medical Group, and employed select providers with Avera McKennan, Sioux Falls, SD and Avera Marshall, Marshall, MN and physicians with hospital privileges at Avera St. Luke's, Aberdeen, SD; Avera Sacred Heart, Yankton, SD; Avera Queen of Peace, Mitchell, SD; Avera St. Mary's, Pierre, SD.

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