Michelle Bryan, MD, PhD - Breast Cancer Surgery - Sioux Falls, SD
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Michelle L. Bryan, MD, PhD

Breast Surgery
4.9 / 5 (Based on 157 Ratings) Read Reviews | Learn More

"I want my patients to know that I'm going to take care of them no matter what, and I want to be a partner in making the best health care decisions for them. The hugs I get from patients, that relationship, is the best part of what I do."

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Office Information

About Me

Are you facing a breast cancer diagnosis? If surgery is in your oncology treatment plan, trust Michelle Bryan, MD, PhD, to be there for you with expert and specialized surgery options. Practicing at Avera Medical Group Comprehensive Breast Care in Sioux Falls, SD, Dr. Bryan works hand-in-hand with your oncology team to ensure the best protocol steps for your individual diagnosis, cancer stage and tumor location.

Expert Surgery Treatments for Breast Cancer

Fellowship-trained, Dr. Bryan works together with world-class breast cancer experts at Avera Medical Group Oncology & Hematology in Sioux Falls, part of the Avera Cancer Institute. With her extensive experience, you can count on Dr. Bryan to recommend the most appropriate, effective breast cancer surgery options for you, while considering the best possible cosmetic results.

Her specialized training in surgical procedures includes:

  • Electron-based intraoperative radiation therapy (IORT) – Includes radiation during surgery which may eliminate the need for additional radiation or shorten the course of radiation
  • Oncoplasty – Combines techniques for removing cancer along with plastic surgery methods to improve the appearance of breasts
  • Lumpectomy – Conserves the breasts while providing the same recurrence prevention as mastectomy
  • Nipple-sparing mastectomy – Preserves the nipple and skin of the breast for future reconstruction
  • Hidden Scar™ – Removes the tumor and a slight amount of surrounding tissue through a small incision

Comprehensive Care for Breast Cancer

Benefit from multidisciplinary approach at Avera, in which a team of breast cancer experts meet weekly to discuss the best treatment options for your specific type of breast cancer. Dr. Bryan also recognizes the benefits of treating the side effects of cancer surgery through integrative medicine, so that you can experience a better quality of life.

“Find joy and gratitude in every moment, as this affects your overall health and life,” she adds as advice to patients facing cancer treatments. She is currently involved in quality performance measures research surrounding the delivery and efficiency of breast cancer surgery, and she participates in ongoing clinical trials at Avera.

Active Lifestyle

In her free time, Dr. Bryan enjoys being outdoors with her husband and son, planting and canning garden produce, raising animals and fostering a strong spiritual environment for her family.



Wake Forest University School of Medicine, Winston-Salem, NC, Medical School


Wake Forest Baptist Health, Winston-Salem, NC, General Surgery


Wake Forest Baptist Health, Winston-Salem, NC, Surgical Education

Cleveland Clinic at Akron General, Akron, OH, Breast Surgery Oncology

Professional Memberships

  • American College of Surgeons
  • American Society of Breast Surgeons

Honors, Awards, etc.

  • PhD - Department of Infectious Diseases and Microbiology, Graduate School of Public Health
  • Academic Entrepreneurship - Joseph M. Katz Graduate School of Business


Eligible - American Board of Surgery


July 30, 2021
I missed seeing the receptionist at the front desk during this visit. She is always so fun and friendly.
July 19, 2021
This is the first time that I had seen Dr. Bryan, and I was impressed with her.
July 16, 2021
Dr. Bryan and the rest of the staff I interacted with were so warm and caring. They treated me as a person, not just a patient.
July 15, 2021
I am thankful that Dr Bryan is always ready to say a prayer when I need it.
July 14, 2021
My experiences at the clinic were very personable and caring from EVERYONE! I received answers to all of my questions from staff as well as from Dr. Bryan. I left the clinic feeling good about this experience and ready for my next step on this journey through cancer. Thank you for this opportunity for me to share my gratitude to all of the
July 10, 2021
The entire staff is amazing.
July 03, 2021
The young lady that did my mammogram ways so kind and such a kind heart first time I have not had to have a ultrasound and biopsy. She understood and embraced the tears of joy.
July 02, 2021
I love your receptionist, she is so nice and welcoming . Your staff are courteous and respectful in an akward situation ie. Shirt off with people touching breasts. Also very honest. I had gained a lot if weight between this appointment and last years appoitment. They encouraged me to drop the weight and exercise. I already knew this, but it was good to have it pointed out directly. Gives incentive to kick it in gear and do something about it.
June 28, 2021
Dr. Bryan took a great amount of time to make sure I understood upcoming procedures and made me feel very confident in my medical Team. I am extremely appreciative!
June 28, 2021
Wonderful caring staff!
June 28, 2021
I was VERY impressed by Dr. Bryan and would trust her completely should I need to utilize her skills as a surgeon in the future.
June 19, 2021
Very impressed with the care I received at Avera. Everyone from the reception area, various technicians, genetics and finally Dr. Bryan were friendly and compassionate...always asking if there were any questions. Felt very comfortable asking for clarification. I have great faith in Dr. Bryan.
June 18, 2021
Very caring and understanding doctor
June 18, 2021
I am so grateful for this team of helpers!!!
June 14, 2021
First time seeing Dr. BRYAN but she was excellent.
June 10, 2021
I was extremely pleased with my treatment and the results I recieved. Thanks so much!!!
June 09, 2021
Everyone was kind and took the time to explain things.
June 09, 2021
I felt very comfortable during my appointment and appreciated the time each person spent with me
June 06, 2021
The team is knowledgeable and kind.
June 01, 2021
I love the professionalism, positive attitudes and Godly spirituality in all of my Avera healthcare providers.
May 29, 2021
I feel the care I receive is not only clinically exceptional but also holistically rendered.
May 22, 2021
She's just a great Dr. all the way a round
May 21, 2021
it was good
May 11, 2021
Everyone I saw that day was very informative and kind. They made you feel truly comfortable. I have nothing but good things to say about my visit there. Thank you for being so caring!
May 10, 2021
Dr Bryan took her time when speaking with me. That has made all the difference.
May 07, 2021
I had a wonderful doctor. Would highly recommend her. So happy i was sent to her.
April 23, 2021
Everyone was very professional and helpful.
April 22, 2021
I was very impressed. Everyone went way above to give me fantastic service
April 07, 2021
We were going to be late because of tire issue and they accomadated us to still make the appointment! Much appreciated!
April 02, 2021
Everybody treated me with respect and care. My Dr. M.Bryan was fantastic. Very passionate about her job to treat and care to her patients. I got the best. So thankful.
March 26, 2021
I wish the clinic was closer - I have an hour or more drive to get there.
March 25, 2021
Everyone was very professional. The computer system seems slow and the exchange of my medical history had to be repeated in each department.
March 25, 2021
Dr Bryan and nurse are quite amazing.!!!!
March 23, 2021
Being newly diagnosed with cancer this was my first trip to dr Bryan and facility! Very impressed and I have absolutely no complaints. Very happy with how things are going and how I am being handles to get through this journey I have never been on. I am a mammographer and now I am a breast cancer patient. I would want to be at no other facility. I truly feel this is where I need to be and have complete confidence in how my treatment plan is being handled.
March 13, 2021
Was very confused when i left my appt...felt as if i wasnt care for like i should've been..left with no answers about my medical condition
March 13, 2021
I appreciate the way Avera coordinates my multiple appointments with the different clinics and servicers so that it can all be handles in on session without multiple returns and visits. IE: mammogram/ ultra sound if necessary/ breast surgeon conference. all taken care of smoothly & efficiently, while everything is still fresh in my mind. thank you. HOWEVER--- I do want Covid gone so I can get a cup of your great coffee :) thank you again
March 12, 2021
Everyone I dealt with was extremely nice & helpful. Really liked Dr. Bryan. She explained everything very well & seemed genuinely interested in finding the best treatment for me.
March 10, 2021
I always receive high quality care from Avera. I am grateful Avera is my healthcare provider.
March 05, 2021
This whole experience for the last almost 2 years has been wonderful..if you consider it pertained to a breast cancer diagnosis and treatment. I was surrounded with the BEST MEDICAL TEAM EVER! I cant pick out just was person..... THEY ALL WERE FABULOUS, CARING, TALENTED individuals! Im sure if i ever need any further medical care....THE AVERA MEDICAL SYSYEM WILL BE MY " FIRST GO TO" health care!! THANK YOU SOO MUCH! KEEP UP THE GREAT WORK!?????
March 04, 2021
Your staff was tremendous
February 28, 2021
The providers were very kind and caring.
February 26, 2021
I am very pleased with the outcome of my treatment by Dr. Bryan. She is a joy to talk to, listens carefully, and explains and answers questions. She makes sure I have all the information I need. Thank you.
February 18, 2021
I loved your services and would recommend to my friends
February 18, 2021
Dr Bryan's prayer to conclude our visit very much appreciated.
February 07, 2021
Everyone was passionate and caring.
February 06, 2021
I have the highest respect and confidence in Dr. Bryan and her staff and am thankful to have her as a care giver
February 03, 2021
On time!
February 03, 2021
Everyone has been so carin, kind. They listen 2 me & ask if theres any questions etc. I feel very comfortable when i go there. Thank you!ke
January 27, 2021
Dr Bryan and the staff are kind and considerate!
January 26, 2021
Thakkfull with the doctors and nurses, I'm happy all nice people
January 23, 2021
Entire team was so pleasant, helpful and knowledable
January 22, 2021
The Avera staff is outstanding in all respects and I am thankful to have the opportunity to be in their care.
January 15, 2021
Everyone was kind - patient - understanding- accommodating! Loved Dr. M Bryan
January 01, 2021
Every single one of the staff were absolutely amazing. I wish I could remember all their names and give them a big shout out and let them know how much I appreciated their professionalism , personalization, and high level of care. All so cheerful , explained everything, made me comfortable on a Day that many would get to go home early for NYE, they did not rush me through but instilled confidence that they cared about my health and well-being. Wish all those that took care of me would know how great they are at their jobs. If you have a way of finding out, give them all a great big kudos, they deserve it!!
December 26, 2020
Even though I had not seen Dr. Bryan for 6 months, her warmth in greeting me and spending all the time I needed with her during my appointment was very much appreciated. She is a true gem!
December 24, 2020
Dr Bryan was the most knowledgeable and caring surgeon I have ever met! Her respect for me as a person and .not just a patient was a beautiful part of her consultation. I have no doubt that I got the best of the best with Dr Bryan. God was present with us as well.
December 22, 2020
I have been very pleased with everyone and the facilities.
December 20, 2020
Avera is top-shelf. Everyone is very caring and considerate
December 19, 2020
I'm happy because all people in the area is very nice
December 15, 2020
Dr. Michelle Bryan was the best doctor I have ever had! She is totally professional while keeping it personal. Highly recommend her!
November 22, 2020
Upon leaving the clinic (with my big pink bag announcing I had cancer), I felt a sense of peace and security....that I could handle this and had great, caring people helping me.
November 21, 2020
The doctor, the receptionists, the nurse and the navigator were the most kind caring people. Couldn't ask for any better treatment.
November 21, 2020
A difficult situation was made so much better by her calm, caring spirit.
November 20, 2020
As always, treatment here is top shelf!
November 20, 2020
Dr. Bryan has to be one of the most caring, compassionate Drs I have ever met. The concern she shows to her patients is unbelievable.
November 15, 2020
Very satisfied with all great people
November 14, 2020
Dr Bryan has a lot of knowledge and I feel very confident with her.
November 14, 2020
All staff were so welcoming and friendly. They worked to accommodate my two appointments so they were scheduled close together as we live 2 1/2 hrs away from SF. Wonderful experience and I will be back every six months.
November 13, 2020
Everyone was very pleasant.
October 19, 2020
Dr Bryan took the time to answer my questions and explain things to me. In addition she was very kind.
October 12, 2020
Excellent care fine facility & staff
October 10, 2020
Post op visit. My surgeon had retired and this surgeon had taken her patients. Considering that this physician had not performed my surgery, I thought she spent much time with me answered questions and gave me pointers to remain healthy.

This directory contains information about the provider members of Independent Health Care Associates, Avera Health and all Avera entities, members of the Avera Medical Group, and employed select providers with Avera McKennan, Sioux Falls, SD and Avera Marshall, Marshall, MN and physicians with hospital privileges at Avera St. Luke's, Aberdeen, SD; Avera Sacred Heart, Yankton, SD; Avera Queen of Peace, Mitchell, SD; Avera St. Mary's, Pierre, SD.

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Avera is a health ministry rooted in the Gospel. Our mission is to make a positive impact in the lives and health of persons and communities by providing quality services guided by Christian values.

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