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Avera Laboratory Network - Sioux Falls

Reference Laboratory resources for our customers and health care providers.

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Patient Resource - Laboratory Locations

Service Location Details & Directions

Avera McKennan Regional Laboratory provides many easy access patient service center locations in Sioux Falls.

View a printable PDF location map or find location details below.

Avera McKennan Hospital & University Health Center - (Main Floor) Drawing Station

1315 S. Cliff Ave. Sioux Falls, SD 57105

  • Hours: This location is open 24 hours a day, seven days a week
  • Location in building: Ground Floor
  • Parking: South or North parking ramp - valet parking use main entrance

Plaza 1 - Laboratory Services

1417 S. Cliff Ave. Sioux Falls, SD 57105

  • Hours: 7 a.m. to 5 p.m. Monday - Friday (no holidays)
  • Location in building: 3rd Floor and take a right
  • Parking: Just outside the building - valet parking use main entrance

Plaza 2 - Laboratory Services

1301 S. Cliff Ave. Sioux Falls, SD 57105

  • Hours: 7 a.m. to 5 p.m. Monday - Friday (no holidays)
  • Location in building: Ground floor within the Imaging Center
  • Parking: Just outside the building - valet parking use main entrance

Plaza 3 - Laboratory Services

1315 S. Cliff Ave. Sioux Falls, SD 57105

  • Hours: 7 a.m. to 5 p.m. Monday - Friday (no holidays)
  • Location in building: 2nd Floor - Skywalk level
  • Parking: South parking ramp

Prairie Center - Laboratory Services

1000 E. Cliff Ave. Sioux Falls, SD 57105

  • Hours: 7:00 a.m. to 4 p.m. Monday - Friday (no holidays)
  • Location in building: Entrance level, across from elevators
  • Parking: Just outside the building - valet parking use main entrance

Avera Medical Group Family Health Center - First Floor

2100 S. Marion Rd. Sioux Falls, SD 57105

  • Hours: 7:30 a.m. to 9 p.m. Monday - Friday
  • 9 a.m. to 6 p.m., Saturday
  • 10 a.m. to 5 p.m., Sundays and holidays
  • Parking: Just outside the building

Avera Specialty Hospital - First Floor

6100 S. Louise Ave. Sioux Falls, SD 57108

  • Hours: 7 a.m. - 5 p.m. Monday-Friday (no holidays)
  • Parking: Just outside the building

Client Resources

Service Overview


Our laboratory consultant staff offers customized consultation services for physician offices, clinics and hospital-based laboratories as well as onsite contracted laboratory management. The consultants are experienced Clinical Laboratory Scientists with many years of laboratory and management experience. They are well versed with CLIA standards, compliance and billing issues as well as with COLA and CAP accreditation requirements. Our consultants will work with your staff to evaluate new laboratory methods or instruments, provide guidance and support for all disciplines of the laboratory, and also offer continuing education through webinars, onsite training, or group events as requested.

ALN-SF provides courier services to our clients in keeping with the highest quality and ethical standards. For those tests that are not performed in our Avera McKennan Laboratory, we utilize Mayo Medical Laboratories and ARUP Laboratory, located at the University of Utah: two of the most prestigious facilities in the United States.

Online Test Ordering and Results Reporting are available through ALN-SD using the Atlas MD Bridge product which can be interfaced to your electronic medical record (EMR). For Eide Bailly accounts, we use the Emdeon Laboratory Order Entry/Results Reporting system that is part of the Intergy Electronic Medical Record Product.

Client Services

Client Services is the primary contact for the laboratory clients and customers, both inpatient and outpatient. This area of the laboratory is staffed by specially trained laboratory professionals whose primary duty is to assist our clients and patients. These Medical Laboratory Technicians have received customer service training. They also make arrangements to connect clients/customers to our professional resources (Pathologists and other laboratory professionals). They answer in excess of 1000 calls per week and average less than 5% dropped calls.

Additionally, Client Services personnel are responsible for packaging and shipping tests performed by referral laboratories, test/specimen/client problem resolution, verbal and electronic communication with customers following established standards and procedures.

Comprehensive Scope of Services

ALN-SF offers an extensive range of testing at the local level to allow rapid turn-around of results. Our scope of services includes much more than testing to support our customers laboratory and facility needs. Additional outreach value-added services that can be custom-designed to meet your specific needs includes:

  • Management & Technical Consultation
  • Regulatory & Accreditation Compliance Guidance
  • Quality Systems development, implementation & reviews
  • Pathologist Clinical Consultants
  • Clinical Laboratory Directorships
  • Continuing Education & Competency Assessment support
  • Courier & Delivery Services

Outreach Courier Service

Outreach Courier Service

Avera partners with MedSpeed, an ISO-certified transportation service provider, to handle your courier needs. Medspeed offers scheduled routes to our high-volume laboratory clients, as well as on-demand services. For information on specimen preparation or processing prior to a courier pick-up, you may access the Online Test Directory or contact ALN-SF Client Services (CS).

Scheduled Services are available Monday-Friday excluding major holidays (New Year’s Day, Memorial Day, July 4th, Labor Day, Thanksgiving Day, Christmas Day).

On-Demand Service for Immediate Needs are available for times when items need to be moved quickly, or on days when you do not have scheduled service. Charges may apply, based on the level of service required and time of request.

Sioux Falls clients - routine non-scheduled pickups:

605-322-7187 opt 2 (CS). If same-day transport is needed, calls must be received by 1245 pm Monday-Friday. Specimens will be picked up before 5 pm.

All clientsexpedited pickups or after hours:

605-322-7187 opt 3 or 1-800-560-4846 opt 3 (Medspeed). Be prepared to give the pick-up location, address, a contact person and a phone number.

Medicare and Compliance

Service Center and Specimen Collection References

Client and Testing Forms

General Information

Client Service Support

Avera McKennan Hospital & University Health Center
1301 S. Cliff Avenue
Sioux Falls, SD, 57117

Client Service Hours

  • Monday-Friday 7:00am-5:00pm
  • Saturday 7:30am-4:00pm
  • Excluding the major holidays (New Years Day, Memorial Day, July 4th, Labor Day, Thanksgiving, Christmas)

Client Support Extended Service Hours:

  • 7 days a week
  • 24 hours a day including major holidays

Moving Health Forward

Avera is a health ministry rooted in the Gospel. Our mission is to make a positive impact in the lives and health of persons and communities by providing quality services guided by Christian values.

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