Avera Pharmacy - Sioux Falls - Louise Avenue
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Alert IconEveryone, age 12 and older, is now eligible for the COVID-19 vaccine. Please visit our vaccination resources for more information.  Masks are required for patients, visitors and vendors to enter our facilities.

6100 S. Louise Ave Suite 1100 Sioux Falls, SD 57108

Hours of Operation

Monday - 8:00AM-5:00PM
Tuesday - 8:00AM-5:00PM
Wednesday - 8:00AM-5:00PM
Thursday - 8:00AM-5:00PM
Friday - 8:00AM-5:00PM

Featured Health Services

Avera Pharmacy

Avera Pharmacy Louise Avenue in Sioux Falls, SD, provides convenient pharmacy services for the public and discharged patients.

Important Service Adjustments

To best protect our patients, our staff and all our families during the COVID-19 pandemic, we encourage you to have your health care provider call, fax, or e-prescribe new and refill prescriptions. Avera Pharmacies also encourage you to use our free mail or shipping options. If you need over-the-counter medications or other items, let us know ahead of time and we can gather those items for you, also. Call your Avera Pharmacy with questions or to arrange for this free service. You can also select shipping in the Avera Rx app.

Located on the first floor of the Avera Specialty Hospital on the Avera on Louise Health Campus, our retail pharmacy is ideally located for both discharging patients and outpatient medication support. We also offer medication support for the nearby Avera Addiction Care Center.

To transfer your prescription, please call 605-504-1351.

Purchase Over-the-Counter Medications 

When you fill a prescription at Avera Pharmacy, order all your over-the-counter medications and supplements for added convenience. Shipping is free on all orders!

Download the Avera Rx App

For a simple and convenient way to manage medications – for your entire family – sign up for AveraRx. With a free AveraRx account, you can easily:

  • Order refills
  • Receive a message when your prescription is ready
  • Set up reminders to take your medications
  • View an up-to-date list of your prescriptions

Download on the App Store

Get it on Google Play

Avera Rx Desktop link button

Already have an AveraRx account? Login from your computer here.

Pharmacy Services

Our pharmacy offers complete prescription services, along with convenient and varied selection of over-the-counter retail products, including a display of available durable medical equipment.

Sign Up for Text Alerts

When you sign up for Avera Pharmacy’s text alerts program, you’ll receive notifications about: 

  • Refill reminders
  • Problems with insurance, inventory issues, etc.
  • Credit card issues
  • Home deliveries on the way
  • Immunization reminders
  • Pick-up reminders

You must sign up for text alerts at your local Avera Pharmacy location and provide your cell phone number.

Dispose of Your Unused Medication

Want to safely throw away unused or expired medications? Learn about blue, drop-off MedSafe receptacles available at most Avera Pharmacy locations during regular pharmacy hours.

Meds to Beds Program

This pharmacy offers the Meds to Beds program for patients discharging after surgical procedures or same-day surgery patients. This convenient pharmacy service is offered to patients during their pre-operation preparation phone call. Patients may choose to update their preferred Avera pharmacy to Avera Pharmacy Louise Avenue, as needed.

To streamline medication delivery, Avera’s registered nurses and pharmacy team work directly with physicians’ orders and patients to deliver needed medication straight to the bedside for patients discharging from the fourth floor—or to have prescriptions ready for pick-up as same-day patients leave after surgery. Please ask your specialist provider or registered nurse for more information, if you have an upcoming surgery at Avera Specialty Hospital.

Specialty Pharmacy Pick-up Location & Mailed Prescription Options

Do you take specialty pharmacy medications? Avera Pharmacy Louise Avenue is an outreach location for specialty pharmacy prescriptions, acting as an additional Avera pick-up location option for your convenience.

Please call our Avera Specialty Pharmacy 24/7 at 605-322-8300 or 855-442-8372 to fill your specialty drug prescription—and let us know how you want to receive your prescription.

We also can mail your prescription to you with free home delivery; registered and trackable mail options are available. Ask our pharmacists about delivery options.

Call Ahead for Your Prescription

Have your prescription ready when you arrive by calling 605-504-1351.

Immunizations & Medication Synchronization Program

This pharmacy offers immunization options to the public. Please call us at 605-504-1351 if you have questions or would like to schedule an immunization for you or your loved one.

For chronic disease management, this pharmacy offers convenient, same-day medication synchronization refills for our clinic patients. Ask your specialist provider if you are eligible to enroll in this pharmacy service, if you have a chronic condition.

Live Better. Live Balanced. Avera.

Avera is a health ministry rooted in the Gospel. Our mission is to make a positive impact in the lives and health of persons and communities by providing quality services guided by Christian values.

© 2021 Avera Health, Sioux Falls, SD. All Rights Reserved.