6100 S. Louise Ave Sioux Falls, SD 57108

Hours of Operation

Sunday - 24 Hours
Monday - 24 Hours
Tuesday - 24 Hours
Wednesday - 24 Hours
Thursday - 24 Hours
Friday - 24 Hours
Saturday - 24 Hours

Visiting Hours
Open Visitation

Surgery Hours
Mon-Fri: 6:30AM-4PM

Lab Hours
Mon-Fri: 7AM-5PM

Avera QuickLabs
Monday-Friday: 8AM-5PM

Retail Pharmacy Hours
Mon-Fri: 8AM-5PM

Restaurant Hours
Mon-Fri: 7AM-2PM

Inpatient Room Service
Daily: 7AM-7PM

Free Valet Parking
Mon-Fri: 7:30AM-4:30PM

Avera Specialty Hospital

Experience the future of health care at the Avera Specialty Hospital and Avera Medical Group clinics. This bold, transformative 260,000-square-foot facility is designed specifically around your needs, houses advanced surgical technology—and is backed by board-certified physicians and staff.

Our Avera mission of treating the mind, body and spirit is reflected throughout the building design—and in the compassionate care we deliver every day. Proudly serving the upper Midwest region, Avera offers comprehensive specialty services to residents of South Dakota, North Dakota, Minnesota, Nebraska and Iowa.

The Avera Specialty Hospital is not a critical care facility, with no emergency room access. Emergency or trauma cases are served by our Avera McKennan Hospital & University Health Center in central Sioux Falls, located on Cliff Avenue, or by Avera Medical Group Family Health Center in west Sioux Falls, located on Marion Road.

Convenient Access to Innovative Health Care

Avera Specialty Hospital and Avera Medical Group clinics are the flagship of the Avera on Louise Health Campus. Located at 69th Street and Louise Avenue in Sioux Falls, SD, this bold, new hospital and clinic building design is revisioning the delivery of health care by focusing on patient convenience.

With close-by roadway and lodging access, the Avera Specialty Hospital and Avera Medical Group clinics are made for convenience with all the amenities expected of a modern health care facility. No matter your health care needs, we’re dedicated to offering inpatient and outpatient services designed to fit you.

Specialty Surgical & Clinical Services

Avera Specialty Hospital and Avera Medical Group clinics feature the compassionate care of Avera’s expert providers and the latest in health care technology for services such as:

You’ll find support services such as on-site laboratory, radiology and imaging including endoscopy, pharmacy, physical therapy and infusion center within walking distance on the ground floor. A separate surgery exit and free valet parking make surgery day more convenient and efficient for patients.

Designed with Patients & Families in Mind

The surgical hospital is connected to medical offices by a beautiful, multi-story commons space filled with natural light where you can relax and enjoy an indoor restaurant called Our Daily Bread, a meditation room and comfortable seating. On the ground level is an outdoor water feature, patio seating area, heated sidewalks and walking path.

Avera Specialty Hospital

  • Avera on Louise

    Avera Specialty Hospital

A Bold New Era of Technology & Amenities

Choose Avera Specialty Hospital for your next inpatient (overnight stay) or outpatient (same-day) surgical procedure.

  • Recover comfortably in our 24-bed hospital on our fourth floor, with walk-in showers, expansive views, a rooftop garden and two family lounges, including one with a fireplace.
  • Eight orthopedic and eight gastroenterology procedure rooms are available on the second and third floors respectively.
  • We offer a trans-formative patient experience in care, with large operating rooms, fully equipped with the latest technology.

Robot-assisted Surgeries & Patient-focus Safety

Robotic-assisted technology for joint replacements increases patient safety and potentially improves patient recovery time. Additional operating room features include:

  • Ultraviolet lights for bacteria reduction
  • State-of-the-art scope cleaning procedures including separate equipment elevators and sterilization processes for increased patient safety

Improving Surgery Day Transitions

Recovery rooms and pre- and post-surgery rooms are planned precisely to help patients transition in and out of surgery care while staying close to family and loved ones.

  • Surgery offers 22 pre- and post-surgery rooms and 11 post-care anesthesia care bays.
  • Gastroenterology has 28 pre- and post-surgery rooms and four recovery rooms.

Revisioning Specialty Clinics

Ask for a referral or visit your specialty physician at the Avera Medical Group clinics. Built-in efficiencies house clinics by discipline on the same floor as respective specialty procedures. We deliberately chose the specialty clinics at the Avera on Louise Health Campus to best serve our regional community and patient population.

  • Avera Orthopedics offers ample exam rooms, multiple radiology rooms, a concussion therapy room and a complete casting room for broken bone repairs. Our team is skilled in complex surgeries and can coordinate all aspects of musculoskeletal care—including sports medicine, joint replacement and bone care.
  • Avera Medical Group Gastroenterology offers spacious exam rooms, along with multiple procedure rooms and several endoscopic procedure suites in the attached hospital. Together with the Avera Digestive Disease Institute, our complete gastroenterology unit delivers a full spectrum of digestive health services, from colorectal cancer screenings to digestive disorder treatment.
  • Avera Medical Group Rheumatology helps diagnose, treat and provide relief for pain or discomfort in muscles, tendons, joints and bones—including the region’s only Gout Clinic.
  • Avera Medical Group Internal Medicine offers adult specialized care for the prevention and treatment of diseases—including long-term management of chronic medical conditions.
  • Avera Medical Group Urogynecology is a specialty that includes both urology and gynecology, with focus on female pelvic floor disorders.

Made for easy navigation, our ground floor includes the majority of our specialty clinics including rheumatology, internal medicine and urogynecology.

Telemedicine at Avera Specialty Hospital and Avera Medical Group clinics offers convenient, immediate access to Avera hospitalist specialists using our innovative telemedicine technology.

Patient Information

The Avera Specialty Hospital has its own dedicated entrance on the south side of the building. Just pull up to the covered entrance and take advantage of free valet parking. An elevator at the entrance will connect you directly to surgical and hospital floors for easy way-finding.

Planning for Your Procedure

The Avera Specialty Hospital has its own dedicated entrance on the south side of the building. Just pull up to the covered entrance and take advantage of free valet parking. An elevator at the entrance will connect you directly to surgical and hospital floors for easy way-finding.

Surgery Day Tips

When you come for your procedure, wear comfortable clothing. Bring all insurance cards and information, as well as a list of your medications and dosages, including supplements, herbal preparations and vitamins.

Also bring any paperwork provided to you by your surgeon. It’s best to leave all valuables at home. If you will have anesthesia (with the exception of local anesthesia), you will need to arrange for a ride home.

Find out how to prepare for your hospital visit at Avera Specialty Hospital, and take advantage of our spiritual care services, and get details on patient responsibilities by downloading our patient handbook in English or en Español.

Volunteer at Avera on Louise

Put your talents, interests and skills to work by volunteering at Avera on Louise Health Campus. You can make a difference by serving in the Avera Specialty Hospital or at our Avera McKennan Hospital & University Health Center, in our clinics or hospice, at Avera Prince of Peace senior living center and in the Sioux Falls community. To learn more about joining our volunteer team, call us at 605-322-7897.

Avera is a health ministry rooted in the Gospel. Our mission is to make a positive impact in the lives and health of persons and communities by providing quality services guided by Christian values.