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To compare the efficacy of nirmatrelvir (PF-07321332)/ritonavir to placebo for the treatment of symptomatic COVID-19 in non- hospitalized pediatric participants with COVID-19 who are at risk of progression to severe disease. Patients are randomized 1:1 and will receive placebo or the investigational product orally for 5 days. Patients will complete in-person and remote follow-up visits including assessments such as nasopharyngeal swabs, blood draws, and physical exams.
This study will determine the effectiveness of a vaccine communication mobile health app on parental decisions to vaccinate their children against COVID-19.