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Safety, tolerability, (PK), pharmacodynamics, and preliminary antitumor activity of BG-68501 in participants with advanced, nonresectable, or metastatic solid tumors.
Ph 1 Open-Label Study Investigate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, & Prelim Antitumor Activity of BGB-B455 in Pts w/Selected Adv/Met Solid Tumors
Goal of trial is to learn if experimental antibody COM701 delays progression of ovarian cancer in Relapsed PSOC. It will also learn about the safety of COM701.
Ph 3 Study of (AZD8205) Monotherapy vs MD’s Choice in Pts w/ B7-H4-Selected Adv/Met Endometrial CA Progressed On/After Platinum-Based Chemo & Anti-PD-1/Anti-PD-L1 Therapy
Ph 3 Study of First-Line Trastuzumab Deruxtecan Monotherapy vs SoC in Pts w/HER2-Expressing (IHC3+/IHC 2+), Mismatch Repair Proficient, Primary Adv/Rec Endometrial Cancer
Trial to evaluate efficacy and safety of T-DXd with bevacizumab vs bevacizumab alone as first-line maintenance therapy in HER2-expressing ovarian cancer
Ph 3, Multicenter,Randomized,Open-label Trial of Trastuzumab Deruxtecan vs SOC Chemo w/wo Radiotherapy as Adj Treatment for HER2-Expressing (IHC 3+/2+) Endometrial Cancer
Ph 2 Trial Evaluating Sapanisertib&Serabelisib (PIKTOR) w/Paclitaxel & Substudy Eval. PIKTOR w/Paclitaxel + Insulin-Suppressing Diet, in Pts w/ Adv/Rec Endometrial Cancer
Phase 3, Ran Placebo-Controlled,Double-Blind, Multicenter Trial of Selinexor in Maint. Therapy After Systemic Therapy for Pt's W/ p53 Wild-Type, Adv./Rec Endometrial Carcinoma
The purpose of this study is to investigate the efficacy and safety of the lifileucel regimen in participants with previously treated endometrial cancer