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This phase III trial studies combination chemotherapy and atezolizumab to see how well it works compared with combination chemotherapy alone in treating patients with stage III colon cancer and deficient deoxyribonucleic acid (DNA) mismatch repair.
This phase III trial studies how well vitamin D3 given with standard chemotherapy and bevacizumab works in treating patients with colorectal cancer that has spread to other parts of the body.
This phase II/III trial studies how well circulating tumor deoxyribonucleic acid (ctDNA) testing in the blood works in predicting treatment for patients with stage IIA colon cancer after surgery.
Evaluate the feasibility of optimizing the safety & tolerability of serabelisib when combined w/ an ISD with a goal of reducing side effects and enhancing anticancer activity
If tucatinib w/ other cancer drugs works better than SOC to treat HER2 positive colorectal cancer. Also looks at side effects that happen with this combination of drugs.
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