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Retail Pharmacy

Take advantage of an Avera retail pharmacy for all of your prescription needs. You’ll also find a wide variety of commonly recommended over-the-counter medications, snacks and more for your convenience.

Expert Care for Your Medications

When you fill your prescriptions at an Avera retail pharmacy, our experienced team of pharmacists will work with your Avera provider to ensure you get the most out of your treatment plan. You’ll also benefit from:

  • Easy order, transfer and refill including the ability to have prescriptions sent to any of our pharmacy locations and refilled using our automated phone system or the new AveraRx app
  • Convenience of being able to pick up your prescription before leaving the hospital/clinic or having them shipped to your home
  • Acceptance of most prescription drug plan and Medicare Part D plans
  • Same insurance co-pay as other pharmacies (some exclusions may apply)
  • $4/$10 generic program
  • Multiple payment options including credit/debit card, personal check, flex spending account and cash

Purchase Over-the-Counter Medications

When you fill a prescription at Avera Pharmacy, order all your over-the-counter medications and supplements for added convenience. Shipping is free on all orders!

Avera Retail Pharmacy Locations

Count on the safe, efficient and convenient management of your prescription medications at Avera retail pharmacy locations in:




Sioux Falls

Dispose of Your Unused Medication

Keep your family and the water supply safe from potentially dangerous drugs. Safely throw away your unused or expired medications, including over-the-counter, controlled or un-controlled drugs at most Avera Pharmacy locations.

Inside the pharmacy, you’ll find a blue MedSafe receptacle where you can conveniently, anonymously dispose of your medicine during regular pharmacy hours. This drop-off receptacle works like a letter box, and is emptied by pharmacy staff.

Place liquid medications of 4 ounces or more in a sealed plastic bag. You may remove Rx labels or black out personal information for privacy. For our staff’s safety, Avera will not accept:

  • Trash
  • Regulated medical waste
  • Sharps
  • Syringes
  • Thermometers
  • Hazardous waste
  • Aerosols such as inhalers
  • Illicit drugs
  • Commercial waste

If you have questions about MedSafe or drug disposal, please call your nearest Avera Pharmacy location.

Donate Unopened, Unused Specialty Medications

Patients can donate specific unused, unopened specialty medications through the Avera Medication Donation Program offered at our Avera Specialty Pharmacy location. Read more about the program and how to donate medications.

Download the Avera Rx App

For a simple and convenient way to manage medications – for your entire family – sign up for AveraRx. With a free AveraRx account, you can easily:

  • Order refills
  • Receive a message when your prescription is ready
  • Set up reminders to take your medications
  • View an up-to-date list of your prescriptions

Download on the App Store

Get it on Google Play

Avera Rx Desktop link button

Already have an AveraRx account? Login from your computer here.

Sign Up for Text Alerts

When you sign up for Avera Pharmacy’s text alerts program, you’ll receive notifications about: 

  • Refill reminders
  • Problems with insurance, inventory issues, etc.
  • Credit card issues
  • Home deliveries on the way
  • Immunization reminders
  • Pick-up reminders

You must sign up for text alerts at your local Avera Pharmacy location and provide your cell phone number.

Pharmacy Residency Opportunities

Avera McKennan Hospital & University Health Center offers pharmacy residency and critical care pharmacy residency programs, based in Sioux Falls, SD.

Read more about our residency programs.

Moving Health Forward

Avera is a health ministry rooted in the Gospel. Our mission is to make a positive impact in the lives and health of persons and communities by providing quality services guided by Christian values.

© 2022 Avera Health, Sioux Falls, SD. All Rights Reserved.