pharmacist preparing prescription.

Specialty Pharmacy Services

Get the specialty medication you need for complex conditions, plus comprehensive service from our accredited pharmacy team.

Our Location New Patients

Avera Specialty Pharmacy is a full-service pharmacy that specializes in filling prescriptions for patients who rely on specialty medications for chronic, rare or complex conditions. These medicines are often high-cost and complex biotech prescriptions requiring special handling, administration or monitoring beyond what a traditional retail pharmacy can provide.

We provide specialty pharmacy services to patients in South Dakota, Minnesota, Iowa, Nebraska, North Dakota, Arizona, Texas and Florida.

Nationally Accredited Specialty Pharmacy

Avera Specialty Pharmacy is nationally accredited by URAC and the Accreditation Commission for Health Care (CHC) – we’re proud to serve our patients by meeting official regulatory requirements and national standards, promoting health care quality through accreditation, education and measurement.

ACHC accredited logo urac accreditation icon

Conditions Needing Specialty Drugs

Medications are considered “specialty” for many reasons. Their complexity might be associated with ingredients, how the patient takes the medicine, the experience and management of medication side effects, cost and/or insurance coverage.

Avera Specialty Pharmacy provides medications for complex conditions such as these and others:

  • Ankylosing spondylitis
  • Asthma
  • Cancer
  • Crohn’s disease
  • Cystic fibrosis
  • Growth hormone deficiency
  • Hemophilia
  • Hepatitis B
  • Hepatitis C
  • Human immunodeficiency virus (HIV)
  • Hyperlipidemia
  • Migraine headaches
  • Movement disorders
  • Multiple sclerosis
  • Psoriasis
  • Psoriatic arthritis
  • Pulmonary arterial hypertension (PAH)
  • Rheumatoid arthritis
  • Osteoporosis
  • Osteoarthritis
  • Solid organ transplant
  • Ulcerative colitis

An Extra Level of Care and Support

Specialty pharmacies are uniquely designed to serve people not just with the medications they need, but also a higher level of comprehensive service. We are part of your larger care team.

Pharmacist Expertise

You’ll work with a pharmacist who is trained in your specific medication. They’ll show you how to take it correctly, monitor drug interactions, discuss potential side effects and answer any questions you have.

Our pharmacists work closely with other members of your care team to ensure you get the most benefit from your prescriptions.

Prior Authorization

We work with your Avera provider’s office to obtain required approval documentation from your insurance company. Our team understands the complicated insurance process and works directly with your insurance company on your behalf.

Benefits Investigation

We collaborate with your provider’s office to verify whether or not insurance covers any prescribed medications. If a prescription is not included under a specific insurance plan, we’ll identify other ways to help get the needed medication. Our diverse network of resources gives us a variety of options to fill prescription orders.

If we cannot fill a prescription and your insurance mandates it be sent to another pharmacy, we’ll notify you and your provider’s office right away and send the prescription to the required pharmacy.

Medication Management

The therapy management program offers personalized education and support from nurses and pharmacists to ensure you receive the most benefits from medication therapy. By choosing to participate in this program, you'll receive:

  • Check-in calls from a nurse case manager knowledgeable about your condition and specialty medication
  • Information about the safe and effective use and handling of your medication
  • Assistance in learning how to take or inject your medications correctly
  • Advice to help prevent and manage medication side effects and injection site reactions
  • Refill reminder phone calls to ensure you always have enough medication on hand

Please note that the program may not cure your condition, and your success depends on your willingness to be engaged in your care.

Assistance Services

Our specialty pharmacy offers a variety of assistive services to support patients. Learn more and contact the pharmacy to request help. 

  • Hearing and Visual Assistance: Communication assistance is available for people who are blind, deaf, deaf-blind, visually impaired or hard of hearing. So that we can communicate effectively together, people with disabilities have free access to these aids and services via audio, video, in person or in writing. Examples include qualified American Sign Language (ASL) interpreters and written translations.
  • Language Interpretation: Communication assistance is available for people with limited English proficiency or who have need for an interpreter or translator. Avera works with virtual and in-person interpreters and contracts with agencies such as Lutheran Social Services and the Multi-Cultural Center.
  • Financial Assistance: As a health care ministry, Avera cares for all patients regardless of ability to pay. If you are experiencing financial hardship, our billing staff is here to discuss payment options to decrease the burden. We treat all patients with dignity and respect. Talk to our pharmacy for support or learn about medication financial assistance options for medication co-pay help through other special programs.

Find a Pharmacy

Learn more about our specialty pharmacy services. Give us a call.

605-322-8300

New Pharmacy Patient Enrollment

We aim to make it as convenient as possible to start getting your prescriptions from our specialty pharmacy. Simply ask your physician to send your prescription by phone, fax or e-prescribe to Avera Specialty Pharmacy. Our staff will call to welcome you to our program and provide important information about your enrollment. We will also:

  • Complete an insurance benefit investigation on your behalf (including Medicare Part D).
  • Coordinate, manage and follow up with insurance benefits so you don’t have to.
  • Obtain prior authorization, if required.
  • Deliver your medication and provide needed medical equipment to you at no extra cost.
  • Help financially challenged patients find support.

Get more details on what to expect and answers to common questions, plus information on patient rights and responsibilities.

Patient Handbook

Manual de paciente en español


Specialty Pharmacy FAQ

How do I check the status of my specialty pharmacy order?

Call us, and our staff will check your medication’s status.

855-442-8372

How does Avera Specialty Pharmacy manage medication delivery?

Specialty medications often require special care. If you would like your medication delivered to your home or a location that’s convenient for you, we will ship it to you for free. With advance notice, we may even be able to ship it to a vacation destination.

  • On Tuesdays through Fridays, medications ordered by 2 PM CT will be available as early as the next day.
  • If your medication is injected, we will include necessary supplies such as needles, syringes and alcohol swabs as required by your therapy.
  • If your medication needs special handling or refrigeration, it will be packaged and shipped accordingly.
  • For some medications, a signature is required upon delivery. If that’s needed for your delivery, our team will inform you in advance.

Inspect your medication delivery immediately to make sure everything that’s needed is inside. If you have questions or need assistance, please call us immediately.

Does Avera Pharmacy participate in medication donation or disposal program?

Yes, Avera Specialty offers donation and disposal programs. We can help of you have unopened, unused medications or want to safely throw away open or expired medications. If you're in need, you can also apply to receive donated medicines.

We Can Help with Specialty Medications

Turn to our team of pharmacists for help with your specialty medication needs.

605-322-8300

Email: SpecialtyRXGeneral@Avera.org

Hospitals, Clinics and Providers: Partner with Avera Specialty Pharmacy

Want to ensure your patients with complex conditions receive more comprehensive care right at the point of care? Partner with Avera Specialty Pharmacy. We’re a health-system-based specialty pharmacy that provides clinical care protocols, specialized data management systems, high-touch service, and collaboration with physicians — all aimed at giving patients the best clinical and financial outcomes.

Additional Features and Benefits

  • Quick and easy ordering by fax, phone or e-prescribing
  • Friendly, local pharmacy staff who are trained in working with specialty medications
  • Prior authorization completion
  • Patient reimbursement assistance to ensure patients receive the maximum benefit from their insurance provider
  • Patient financial assistance to identify additional payment resources to reduce patient financial burden
  • Medication adherence monitoring to ensure the patient is taking the medication correctly
  • Medication side-effect monitoring to communicate any issues the patient may experience while taking the prescription
  • Patient education materials to improve patient understanding of the medication’s purpose
  • Refill reminders to patients to ensure timely medication availability
  • Clinical support to help physicians streamline the care delivery process
  • Interdisciplinary team member involvement to assist physicians in their patients’ care plans
  • Free, overnight shipping in a temperature-controlled package to the location of choice
  • 24-hour, on-call pharmacist available to answer medication questions
  • Lab monitoring

605-322-8300

Email: SpecialtyRXGeneral@Avera.org

woman using the Avera MyChart app on her phone.

Avera Pharmacy in Avera MyChart

With Avera MyChart, you can manage your prescriptions and refills with Avera Pharmacy directly in the same patient portal where you navigate care with Avera providers. No extra app or login is needed for prescription management, including those from the specialty pharmacy.

  • See all medications on your chart from your providers.
  • Request refills from Avera Pharmacy.
  • Sign up for email or text alerts about prescriptions you fill with Avera Pharmacy.

Access MyChart online or on your mobile device.

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MyChart Help for Prescription Features